1. project background and objectives:.
Antibiotics have played a revolutionary role in medicine and agriculture and have become indispensable in the treatment of infectious diseases and disorders. However, in recent years, inappropriate use and over-administration of antibiotics has led to the rapid expansion of resistant strains of bacteria, which has become a serious public health risk worldwide.

Currently, as existing antibiotics become less effective, the development of new antibiotics has not kept pace. In addition, the spread of resistant genes is rapidly progressing across countries, increasing the potential for this to become a new infectious disease threat. Antibiotic resistance is shaking the foundations of modern medicine and agriculture, and without new treatments, the basis for treating infectious diseases is at stake.

2. current research and public opinion:.
The latest research indicates that difficulties in the proper use of antibiotics, especially in the medical establishment, and the gap between patient and physician perceptions are contributing to the rapid spread of resistant strains of bacteria. At the same time, it highlights the reality that inappropriate prescribing of antibiotics leads to drug abuse, which in turn contributes to the progression of resistance.

Meanwhile, international public opinion has focused attention on the issue of antibiotic resistance. The international threat of infectious diseases and the spread of resistant strains are recognized as global issues, and cooperation from the international community is required. In addition, although research on new treatment methods is underway, few have yet been established, and urgent countermeasures are required.

3. problems that have arisen:.
Recent cases of infections caused by resistant strains are difficult to treat and increasingly dangerous to patients' lives. Frequent use of antibiotics in the livestock industry has also contributed to the spread of resistant strains in livestock products, which poses a threat to food safety.

4. reaffirmation of project objectives:.
The objective of this project is to address these issues, develop a comprehensive strategy for the appropriate use of antibiotics and prevention of the spread of resistance, and to produce feasible results through international collaboration. Without our joint efforts, serious limitations in the treatment of future infectious diseases and disease control in agriculture could result.

Project Goals:.

Optimize the use of antibiotics and develop guidelines for their appropriate use
Establish antibiotic resistance surveillance system and early detection of new resistant strains
Tracking of resistance gene spread patterns and development of countermeasures
Conduct educational outreach on antibiotic use in health care institutions and agriculture

Deliverables:.

Use guideline document: up-to-date and comprehensive guidelines for the appropriate use of antibiotics
Resistance Surveillance Database: International antibiotic resistance surveillance database
Resistance gene spread maps: Maps showing patterns of spread of resistance genes
Educational Program Materials: Materials for educational programs on antibiotic use for health care providers and farmers